This book gathers original peer-reviewed papers reporting on innovative methods and tools in design, modeling, simulation and optimization, and their applications in engineering design, manufacturing, and other relevant industrial sectors. Based on contributions to the Third International Conference on Design Tools and Methods in Industrial Engineering, 2023, held on September 6–8, 2023, in Florence, Italy, and organized by the Italian Association of Design Methods and Tools for Industrial Engineering, and the Department of Industrial Engineering of the University of Florence, this first volume of a 2-volume set focuses on advances in design for additive manufacturing, engineering methods in medicine, -centred design, and industrial design and ergonomics. Further topics include design for sustainability, engineering education, experimental methods for product development, and advanced methods for   product and process design. This book provides academicsand professionals with a timely overview and extensive information on trends and technologies in industrial design and manufacturing.